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Fusion Proteins

Researchers' work from Guangzhou University, Department of Internal Medicine focuses on fusion proteins

Published in Gene Therapy Weekly, October 11th, 2007

New research, 'Secretion expression and activity assay of a novel fusion protein of thrombopoietin and interleukin-6 in Pichia pastoris,' is the subject of a report. According to a study from Guangzhou, People's Republic of China, "Thrombopoietin (TPO) is an important haematopoietic factor in megakaryocytic activities as well as in platelet production. Interleukin 6 (IL-6) can co-stimulate TPO-dependent formation of colony forming unit of megakaryocyte (CFU-Meg) growth which could be responsible for residual platelet formation in TPO-deficient or c-mpl-deficient animals."

"In this report, we demonstrated the development of a high-level expression system to produce a...

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