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Gene Therapy

Data on gene therapy reported by researchers at National Institute of Neurological Disorders and Stroke

Published in Gene Therapy Weekly, October 11th, 2007

Fresh data on gene therapy are presented in the report 'Expression of interleukin-13 receptor alpha2 in glioblastoma multiforme: implications for targeted therapies.' "Glioblastoma multiforme is the most common primary malignant brain tumor and despite treatment with surgery, radiation, and chemotherapy, the median survival of patients with glioblastoma multiforme is approximately 1 year. Glioblastoma multiforme explants and cell lines have been reported to overexpress the interleukin-13 receptor alpha2 subunit (IL13Ralpha2) relative to nonneoplastic brain," researchers in the United States report.

"Based on this finding, a recombinant cytotoxin composed of IL13 ligand...

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