Gene Therapy
Research on gene therapy detailed by scientists at Institute Pasteur
Published in Gene Therapy Weekly, October 18th, 2007
Investigators publish new data in the report 'Expression and purification in high yield of a functionally active recombinant human Type I inositol(1,4,5)P3 5-phosphatase.' "Inositol polyphosphates are the most widespread second messenger molecules in eukaryotic cells. Human Type I inositol 1,4,5-triphosphate (Ins(1,4,5)P(3)) 5-phosphatase removes the D-5 position phosphate from soluble Ins(1,4,5)P(3,) a key event in cell signaling particularly in Ca(2+) homeostasis," scientists in Lille, France report.
"In this study, the cDNA encoding human Type I Ins(1,4,5)P(3) 5-phosphatase was subcloned into a modified pMAL expression vector. This plasmid produces a recombinant...
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Source: Gene Therapy Weekly (2007-10-18)
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