Gene Therapy
New Gene Therapy research from C. Escartin et al outlined
Published in Gene Therapy Weekly, October 18th, 2007
"In pathological situations, astrocytes are activated but the consequences on brain energy metabolism are still poorly characterized. We found that local lentiviral-mediated gene transfer of ciliary neurotrophic factor (CNTF), a cytokine known to activate astrocytes, induced a stable decrease in the glycolytic flux in the rat striatum in vivo as measured by 2-[F-18]2-deoxy-D-glucose autoradiography and micro-positron emission tomography imaging. The...
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Source: Gene Therapy Weekly (2007-10-18)
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