RNA Research

Studies in the area of RNA Research reported from Harvard University

Published in Gene Therapy Weekly, October 18th, 2007

"in plants and in the nematode Caenorhabditis elegans, an RNAi signal can trigger gene silencing in cells distant from the site where silencing is initiated. In plants, this signal is known to be a form of dsRNA, and the signal is most likely a form of dsRNA in C elegans as well," scientists in the United States report.

"Furthermore, in C elegans, dsRNA present in the environment or expressed in ingested bacteria is sufficient to trigger RNAi (environmental RNAi). Ingestion and soaking delivery of dsRNA has also been described for other invertebrates. Here we report the identification and characterization of SID-2, an intestinal luminal transmembrane protein required...

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Source: Gene Therapy Weekly (2007-10-18)

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