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Cancer Gene Therapy

Study results from Y. Zhou and colleagues broaden understanding of cancer gene therapy

Published in Gene Therapy Weekly, October 18th, 2007

Scientists discuss in 'IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells' new findings in cancer gene therapy. According to recent research published in the journal Cytokine, "Inflammatory processes are implicated in gastric cancer development. In contrast, the role of inflammation and proinflammatory cytokines in established cancer remains to be clarified."

"We investigated the contribution of IL-17A versus IL-17F-mediated intracellular signalling pathways in human gastric adenocarcinoma AGS cells. IL-8 secretion was evaluated by ELISA,...

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