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Molecular Microbiology

Studies from P. Vasudevan and co-authors have provided new information about molecular microbiology

Published in Gene Therapy Weekly, November 1st, 2007

Scientists discuss in 'Spore cortex formation in Bacillus subtilis is regulated by accumulation of peptidoglycan precursors under the control of sigma K' new findings in molecular microbiology. "'The bacterial endospore cortex peptidoglycan is synthesized between the double membranes of the developing forespore and is required for attainment of spore dehydration and dormancy. The Bacillus subtilis spoVB, spoVD and spoVE gene products are expressed in the mother cell compartment early during sporulation and play roles in cortex synthesis," scientists in the United States report.

"Here we show that mutations in these genes block synthesis of cortex peptidoglycan and cause...

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