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Pneumonia

New pneumonia study findings have been reported by M. Gereke and co-researchers

Published in Gene Therapy Weekly, November 1st, 2007

"' Although the contribution of alveolar type II epithelial cell (AEC II) activities in various aspects of respiratory immune regulation has become increasingly appreciated, our understanding of the contribution of AEC II transcriptosome in immunopathologic lung injury remains poorly understood. We have previously established a mouse model for chronic T cell-mediated pulmonary inflammation in which influenza hemagglutinin (HA) is expressed as a transgene in AEC II, in mice expressing a transgenic T cell receptor specific for a class II-restricted epitope of HA," scientists writing in the journal Respiratory Research report.

"Pulmonary inflammation in these mice...

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