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Protein Therapies

Research from Shandong University provides new data on protein therapies

Published in Gene Therapy Weekly, November 1st, 2007

"'Establishment of functional and stable collaterals in the ischemic myocardium is crucial to restoring cardiac function after myocardial infarction. Here, we show that only dual delivery of a combination of angiogenic and arteriogenic factors to the ischemic myocardium could significantly reestablish stable collateral networks and improve myocardial perfusion and function," researchers in Jinan, People's Republic of China report.

"A combination of FGF-2 with PDGF-BB, two factors primarily targeting enclothelial cells and vascular smooth muscle cells, remarkably promotes myocardial collateral growth and stabilizes the newly formed collateral networks, which...

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