Gene Therapy
New findings from Yale University in the area of gene therapy published
Published in Gene Therapy Weekly, November 1st, 2007
New investigation results, 'Role of hypoxia-inducible transcription factors 1alpha and 2alpha in the regulation of plasminogen activator inhibitor-1 expression in a human trophoblast cell line,' are detailed in a study published in Placenta. "'The plasminogen activator inhibitors (PAIs) play critical roles in regulating hemostatic and invasive functions of trophoblasts through suppression of plasmin-dependent fibrinolysis and extracellular matrix degradation. The expression of PAI-1 is increased under hypoxic conditions, although the mechanism remains incompletely understood," researchers in the United States report.
"In the current study we used HTR-8/SVneo...
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Source: Gene Therapy Weekly (2007-11-01)
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