Gene Therapy
Research from Medical Research Council Cancer Cell Unit reveals new findings on gene therapy
Published in Gene Therapy Weekly, November 1st, 2007
Investigators publish new data in the report 'An increase in DNA double-strand breaks, induced by Ku70 depletion, is associated with human papillomavirus 16 episome loss and de novo viral integration events.' According to recent research from Cambridge, the United Kingdom, "'Integration of human papillomavirus type 16 (HPV16) is a common event in cervical carcinogenesis, although mechanisms of integration are poorly understood. We have tested the hypothesis that an increased number of DNA double-strand breaks (DSBs) affect HPV16 episome maintenance and integration in cervical keratinocytes."
"Increased DSBs were generated over prolonged periods of up to 50 population...
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Source: Gene Therapy Weekly (2007-11-01)
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