Heart Disease

New research on heart disease from Mayo Clinic summarized

Published in Gene Therapy Weekly, November 8th, 2007

"Objectives: Bicuspid aortic valve is a common condition and is associated with a significantly increased risk of developing thoracic aortic aneurysms and acute aortic dissection. specific prediction of the risk of developing thoracic aortic aneurysm, however, is imprecise," scientists writing in the Journal of Thoracic and Cardiovascular Surgery report.

"We hypothesize that genotypic variations in patients with bicuspid aortic valves contribute to this observed variability in aortic phenotype. We, therefore, investigated the potential relationship between mutations in regions of NOTCH1 recently reported to be associated with bicuspid aortic valve and the...

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Source: Gene Therapy Weekly (2007-11-08)

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