Cancer Gene Therapy
New cancer gene therapy study findings have been reported by researchers at Kanazawa University
Published in Gene Therapy Weekly, November 8th, 2007
New research, 'Copper efflux transporter (ATP7B) contributes to the acquisition of cisplatin-resistance in human oral squamous cell lines,' is the subject of a report. "Acquired resistance to cisplatin (CDDP) is an issue in cancer chemotherapy. This resistance has been reported to be correlated with the expression of the Cu influx copper transporter 1 (CTR1) and two copper efflux transporters (ATP7A, ATP7B)," investigators in Ishikawa, Japan report.
"We investigated the correlation between the expression of these transporters and the sensitivity to CDDP using three pairs of parent cell lines and resistant cell lines derived from various types of invasive oral squamous...
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Source: Gene Therapy Weekly (2007-11-08)
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