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Seoul National University, Department of Urology describes research in gene therapy

Published in Gene Therapy Weekly, November 15th, 2007

A report, 'Gene transfer of the K(ATP) channel restores age-related erectile dysfunction in rats,' is newly published data in BJU International. In this recent report, researchers in Seoul, Korea conducted a study "To determine if gene transfer of the ATP-sensitive potassium (K(ATP)) channel can reverse age-related erectile dysfunction in the rat, as the K(ATP) channel is an important subtype of potassium channels regulating smooth muscle tone In an in vitro study, gene were transferred using cDNA of the K(ATP) channel in cultured human corporal smooth muscle (CSM) cells and human embryonic kidney (HEK) cells. After gene transfer, the activities of transferred channels were assessed...

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