RNA Research
Study results from National Institute of Diabetes broaden understanding of RNA research
Published in Gene Therapy Weekly, November 15th, 2007
Research findings, 'RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis,' are discussed in a new report. According to recent research published in the journal Nature Genetics, "Premature fusion of one or more of the cranial sutures (craniosynostosis) in humans causes over 100 skeletal diseases, which occur in 1 of approximately 2,500 live births. Among them is Apert syndrome, one of the most severe forms of craniosynostosis, primarily caused by missense mutations leading to amino acid changes S252W or P253R in fibroblast growth factor receptor 2 (FGFR2)."
"Here we show that a small hairpin...
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Source: Gene Therapy Weekly (2007-11-15)
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