Gene Therapy

Reports summarize gene therapy research from University of Michigan, Kresge Hearing Research Institute

Published in Gene Therapy Weekly, November 15th, 2007

Researchers detail in 'Manipulating cell cycle regulation in the mature cochlea,' new data in gene therapy. According to a study from the United States, "Sensorineural hearing loss, which is often caused by degeneration of hair cells in the auditory epithelium, is permanent because lost hair cells are not replaced. Several conceptual approaches can be used to place new hair cells in the auditory epithelium."

"One possibility is to enhance proliferation of non-sensory cells that remain in the deaf ear and induce transdifferentiation of some of these cells into the hair cell phenotype. Several genes, including p27(Kip1), have been shown to regulate proliferation and...

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Source: Gene Therapy Weekly (2007-11-15)

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