Gene Therapy

Study results from RIKEN broaden understanding of gene therapy

Published in Gene Therapy Weekly, November 22nd, 2007

Researchers detail in 'Mechanisms for asporin function and regulation in articular cartilage,' new data in gene therapy. According to a study from Tokyo, Japan, "Osteoarthritis (OA), the most prevalent form of skeletal disease, represents a leading cause of disability following middle age. OA is characterized by the loss of articular cartilage; however, the details of its etiology and pathogenesis remain unclear."

"Recently, we demonstrated a genetic association between the cartilage extracellular matrix protein asporin and OA (Kizawa, H., Kou, I., Iida, A., Sudo, A., Miyamoto, Y., Fukuda, A., Mabuchi, A., Kotani, A., Kawakami, A., Yamamoto, S., Uchida, A., Nakamura,...

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Source: Gene Therapy Weekly (2007-11-22)

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