Myelodysplastic Syndrome Genetics
Reports from Heinrich-Heine University, Institute of Human Genetics and Anthropology describe recent advances in myelodysplastic syndrome genetics
Published in Gene Therapy Weekly, November 22nd, 2007
Researchers detail in 'Molecular definition of chromosome arm 5q deletion end points and detection of hidden aberrations in patients with myelodysplastic syndromes and isolated del(5q) using oligonucleotide array CGH,' new data in myelodysplastic syndrome. "Isolated deletions of the long arm of chromosome 5, del(5q), are observed in 10% of myelodysplastic syndromes (MDS) and are associated with a more favorable prognosis, although the clinical course varies considerably. If one or more additional chromosomal aberrations are present, this correlates with a significantly shorter overall survival," scientists writing in the journal Genes, Chromosomes, and Cancer report.
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Source: Gene Therapy Weekly (2007-11-22)
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