Chronic Lymphocytic Leukemia Genetics
Reports from University of Nebraska add new data to research in chronic lymphocytic leukemia genetics
Published in Gene Therapy Weekly, November 22nd, 2007
Investigators publish new data in the report 'ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia.' According to a study from the United States, "In B-cell chronic lymphocytic leukemia (CLL), high CD38 expression has been associated with unfavorable clinical course, advanced disease, resistance to therapy, shorter time to first treatment, and shorter survival. However, the genes associated with CLL patient subgroups with high and low CD38 expression and their potential role in disease progression is not known To identify the genes associated with the clinical disparity in CLL patients with high versus low CD38 expression, transcriptional...
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Source: Gene Therapy Weekly (2007-11-22)
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