Gene Therapy

Research on gene therapy detailed by H.J. Pyo and co-authors

Published in Gene Therapy Weekly, November 29th, 2007

According to a study from South Korea, "The differentiation of water-conducting tracheary elements (TEs) is the result of the orchestrated construction of secondary wall structure, including lignification, and programmed cell death (PCD), including cellular autolysis. To understand the orchestrated regulation of differentiation of TEs, we investigated the regulatory mechanism of gene expression directing TE differentiation."

"Detailed loss-of-function and gain-of-function analyses of the ZCP4 (Zinniacysteine protease 4) promoter, which confers TE-specific expression, demonstrated that a novel 11-bp cis-element is necessary and sufficient for the immature TE-specific...

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Source: Gene Therapy Weekly (2007-11-29)

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