Gene Therapy

Study data from University of California, Department of Medicine update understanding of gene therapy

Published in Gene Therapy Weekly, November 29th, 2007

Data detailed in 'Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages' have been presented. According to a study from the United States, "It was reported recently that the cystic fibrosis transmembrane conductance regulator (CFTR) is required for acidification of phagosomes in alveolar macrophages (Di, A., Brown, M. E., Deriy, L. V., Li, C., Szeto, F."

"L., Chen, Y., Huang, P., Tong, J., Naren, A. P., Bindokas, V., Palfrey, H. C., and Nelson, D. J. (2006) Nat. Cell Biol. 8, 933-944). Here we determined whether the CFTR chloride channel is a generalized pathway for chloride entry into phagosomes in macrophages and...

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Source: Gene Therapy Weekly (2007-11-29)

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