Gene Therapy
Scientists at University Zurich target gene therapy
Published in Gene Therapy Weekly, December 6th, 2007
Research findings, 'Thermodynamics of b-HLH-LZ protein binding to DNA: the energetic importance of protein-DNA contacts in site-specific E-box recognition by the complete gene product of the Max p21 transcription factor,' are discussed in a new report. According to a study from Zurich, Switzerland, "The Myc/Mad/Max network of dimeric basic region-helix-loop-helix-leucine zipper (b-HLH-LZ) transcription factors bind to enhancer box sequences (E-box) in the promotors of a large set of genes that control cell metabolism, proliferation, and differentiation. Max (Myc-associated factor X) is the obligate heterodimerization partner of Myc and Mad proteins."
"On the other hand,...
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Source: Gene Therapy Weekly (2007-12-06)
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