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Hematopoietic

Research from University of Pittsburgh, Pittsburgh Cancer Institute provides new data on hematopoietic

Published in Gene Therapy Weekly, December 6th, 2007

Researchers detail in 'Overexpression of the MnSOD transgene product protects cryopreserved bone marrow hematopoietic progenitor cells from ionizing radiation,' new data in hematopoietic. "We determined whether manganese superoxide dismutase (MnSOD)-plasmid liposome (PL) transfection of C57BL/ 6NHsd mouse bone marrow protected cells irradiated at room temperature (24 degrees C) or in the cryopreserved state. MnSOD-overexpressing hematopoietic progenitor 2C6 cells were radioresistant compared to the parent 32D cl 3 cells when irradiated frozen or at 24 degrees C," researchers in the United States report.

"Fresh whole marrow from mice injected intravenously with MnSOD-PL...

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