Hematopoiesis
Recent studies from University of Tokyo add new data to hematopoiesis
Published in Gene Therapy Weekly, December 6th, 2007
"We propose a novel method for the efficient production of hematopoietic progenitors from human embryonic stem cells (hESC) via coculture with murine fetal liver-derived stromal cells, in which embryonic hematopoiesis dramatically expands at midgestation. We generated various hematopoietic progenitors in coculture, and this hematopoietic activity was concentrated in cobblestone-like cells derived from differentiated hESC," researchers in Tokyo, Japan report.
"The cobblestone-like cells mostly expressed CD34 and retained an endothelial cell potential. They also contained hematopoietic colony-forming cells, especially erythroid and multilineage colony-forming cells at...
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Source: Gene Therapy Weekly (2007-12-06)
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