Life Sciences
Data on life sciences discussed by Y. Akamatsu and colleagues
Published in Gene Therapy Weekly, December 6th, 2007
Fresh data on life sciences are presented in the report 'Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies.' "We have developed a mammalian cell surface display vector, suitable for directly isolating IgG molecules based on their antigen-binding affinity and biological activity. Using an Epstein-Barr virus-derived episomal vector, antibody libraries are displayed as whole IgG molecules on the cell surface and screened for specific antigen binding by a combination of magnetic beads and fluorescence-activated cell sorting," scientists in the United States report.
"Plasmids encoding antibodies...
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Source: Gene Therapy Weekly (2007-12-06)
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