Cancer Gene Therapy
Data on cancer gene therapy detailed by researchers at National Center for Cell Science
Published in Gene Therapy Weekly, December 6th, 2007
New research, 'Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation,' is the subject of a report. According to recent research from India, "The p53 protein has been a subject of intense research interest since its discovery as about 50% of human cancers carry p53 mutations. Mutations in the p53 gene are the most frequent genetic lesions in breast cancers suggesting a critical role of p53 in breast cancer development, growth and chemosensitivity."
"This report describes the derivation and characterization of MCF-7As53, an isogenic cell line derived from MCF-7 breast carcinoma...
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Source: Gene Therapy Weekly (2007-12-06)
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