Arthritis
Research from University of Sydney broadens understanding of arthritis
Published in Gene Therapy Weekly, December 13th, 2007
In this recent study, researchers in Australia conducted a study "To investigate the in vitro effect of activated protein C (APC), a natural anticoagulant and novel antiinflammatory agent, on the regulation of the gelatinases matrix metalloproteinase 2 (MMP-2) and MMP-9. Synovial fibroblasts and peripheral blood monocytes isolated from patients with rheumatoid arthritis (RA) or osteoarthritis (OA) and Mono Mac6 cells were used in this study."
"After treatment, cells and culture supernatants were collected for zymography, enzyme-linked immunosorbent assay, reverse transcription-polymerase chain reaction, and Western blot analysis. Fibroblasts and monocytes from RA...
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Source: Gene Therapy Weekly (2007-12-13)
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