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Gene Therapy

Findings in gene therapy reported from Boston University

Published in Gene Therapy Weekly, December 27th, 2007

"The goal of synthetic biology is to design and construct biological systems that present a desired behavior. The construction of synthetic gene networks implementing simple functions has demonstrated the feasibility of this approach," scientists writing in the journal Bioinformatics report.

"However, the design of these networks is difficult, notably because existing techniques and tools are not adapted to deal with uncertainties on molecular concentrations and parameter values. We propose an approach for the analysis of a class of uncertain piecewise-multiaffine differential equation models. This modeling framework is well adapted to the experimental data...

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