Cancer Gene Therapy

Study data from University of Hong Kong, Department of Surgery update understanding of cancer gene therapy

Published in Gene Therapy Weekly, December 27th, 2007

Scientists discuss in 'Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells' new findings in cancer gene therapy. According to recent research from People's Republic of China, "Previously, we showed that down-regulation of claudin-10 (CLDN-10) in hepatocellular carcinoma is associated with prolonged disease-free survival after curative surgery. Claudins are important tight junction components."

"Increasing evidence shows that claudins are involved in cancer progression but each member of claudins is specifically expressed in a variety of malignancies. The biological role of CLDN-10 in hepatocellular carcinoma is unexplored. In the...

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Source: Gene Therapy Weekly (2007-12-27)

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