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Gene Therapy

Data on gene therapy published by researchers at University of Bergen, Department of Biomedicine

Published in Gene Therapy Weekly, January 3rd, 2008

Data detailed in 'Normal brain cells contribute to the bystander effect in suicide gene therapy of malignant glioma' have been presented. According to recent research published in the journal Clinical Cancer Research, "Lentiviral vectors pseudotyped with glycoproteins of the lymphocytic choriomeningitis virus (LCMV-GP) are promising candidates for gene therapy of malignant glioma, as they specifically and efficiently transduce glioma cells in vitro and in vivo. Here, we evaluated the therapeutic efficacy of LCMV-GP and vesicular stomatitis virus glycoprotein (VSV-G) pseudotyped vectors."

"Therapeutic efficacy was tested for unmodified (9L) and DsRed-modified...

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