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Gene Therapy

New gene therapy study results reported from N. Duale et al

Published in Gene Therapy Weekly, January 10th, 2008

"Testicular germ cell tumors (TGCTs) respond well to cisplatin-based chemotherapy and show a low incidence of acquired resistance compared to most somatic tumors. The reasons for these specific characteristics are not known in detail but seem to be multifactorial," researchers in Oslo, Norway report.

"We have studied gene expression profiles of testicular and colon cancer derived cell lines treated with cisplatin. The main goal of this study was to identify novel gene expression profiles with their functional categories and the biochemical pathways that are associated with TGCT cells' response to cisplatin. Genes that were differentially expressed between the TGCT cell...

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