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Cancer

Research on cancer described by scientists at University of Parma

Published in Gene Therapy Weekly, January 17th, 2008

According to recent research from Parma, Italy, "Besides a fully processed, secreted form of clusterin (sCLU), an alternative proapoptotic form of the protein targeting the nucleus (nCLU) was recently described."

"The possible differential roles played by the two clusterin forms in growth and motility of nonmalignant and malignant prostate cells are investigated here. sCLU or nCLU was transiently transfected in both androgen-independent prostate cancer cells (PC3 and DU 145) and immortalized prostate epithelial cells (PNT1A, a nontumoral control)," wrote R.M. Moretti and colleagues, University of Parma.

The researchers concluded: "Then, cell growth,...

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