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Gene Therapy

New findings from Uludag University, Medical Department describe advances in gene therapy

Published in Gene Therapy Weekly, January 17th, 2008

"Familial adenomatous polyposis, an autosomal-dominant disease characterized by the presence of 100 or more colorectal adenomatous polyps, results from mutations in the adenomatous polyposis coli tumor suppressor gene. This study was designed to investigate adenomatous polyposis coli gene mutations in members of Turkish families with familial adenomatous polyposis to constitute an adenomatous polyposis coli mutation spectrum for the Turkish population and to determine specific biomarkers for use in the early diagnosis of familial adenomatous polyposis," investigators in Bursa, Turkey report.

"We investigated adenomatous polyposis coli gene mutations in six unrelated...

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