Hepatocellular Cancer
New hepatocellular cancer study results from Osaka University, Department of Molecular described
Published in Gene Therapy Weekly, January 24th, 2008
Investigators publish new data in the report 'A high expression of GDP-fucose transporter in hepatocellular carcinoma is a key factor for increases in fucosylation.' "Changes in the levels of fucosylation regulate the biological phenotype of cancer cells and a specific fucosylation, such as fucosylated alpha-fetoprotein (AFP-L3) has been clinically used as a tumor marker for hepatocellular carcinoma (HCC). However, detailed molecular mechanisms that explain the increased fucosylation in HCC remain unknown despite 10 years of study by these researchers," scientists in Suita, Japan report.
"Fucosylation is regulated by complicated mechanisms that involve several factors:...
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Source: Gene Therapy Weekly (2008-01-24)
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