Life Sciences
New findings from P. Bai and co-authors in the area of life sciences published
Published in Gene Therapy Weekly, February 7th, 2008
Data detailed in 'Peroxisome proliferator-activated receptor (PPAR)-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/PPARgamma heterodimer' have been presented. "The peroxisome proliferator-activated receptor-gamma (PPARgamma, NR1C3) in complex with the retinoid X receptor (RXR) plays a central role in white adipose tissue (WAT) differentiation and function, regulating the expression of key WAT proteins. In this report we show that poly(ADP-ribose) polymerase-2 (PARP-2), also known as an enzyme participating in the surveillance of the genome integrity, is a member of the PPARgamma/RXR transcription...
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Source: Gene Therapy Weekly (2008-02-07)
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