Published in Gene Therapy Weekly, February 7th, 2008
"Using both a quantitative assay of intracellular cholesterol and an [H-3] -labeled cholesterol efflux assay, we studied the effect of sirolimus on cholesterol accumulation and cholesterol efflux in HepG2 cells in the absence or presence of inflammatory stress induced by interleukin-1 beta. The gene and protein expression of molecules involved in cholesterol homeostasis were...
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