Cancer Vaccines

Research on cancer vaccines published by scientists at Niigata University, Medical Department

Published in Gene Therapy Weekly, February 14th, 2008

"Tumour-draining lymph node T cells are an excellent source of effector T cells that can be used in adoptive tumour immunotherapy because they have already been sensitized to tumour-associated antigens in vivo. However, such tumour-specific immune cells are not readily obtained from the host due to poor immunogenicity of tumours and reduced host immune responses," scientists in Niigata, Japan report.

"One obstacle in implementation of adoptive immunotherapy has been insufficient sensitization and expansion of turnour-specific effector cells. In this study, we aim to improve adoptive immunotherapy by generating anti-tumour effector T cells from naive T lymphocytes. We...

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Source: Gene Therapy Weekly (2008-02-14)

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