Enzyme Therapy
Researchers from Shinshu University, Medical Department describe findings in enzyme therapy
Published in Gene Therapy Weekly, February 21st, 2008
"Bifidobacteria are nonpathogenic, anaerobic domestic bacteria with health-promoting properties for the host. In our previous study, Bifidobacterium longum (B. longum) were found to be localized selectively and to proliferate within solid tumors after systemic application. Additionally, B. longum transformed by shuttle-plasmid including the cytosine deaminase (CD) gene expressed active CD, converted the prodrug 5-fluorocytosine (5-FC) to 5-fluorouracil (5-FU)," researchers in Matsumoto, Japan report.
"We also demonstrated antitumor efficacy with a transformant of B. longum in rats. In this study, we found that Bifidobacterium breve (B. breve), the smallest species of...
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Source: Gene Therapy Weekly (2008-02-21)
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