Gene Therapy
Data from University of Ljubljana provide new insights into gene therapy
Published in Gene Therapy Weekly, February 21st, 2008
"As an alternative to viral methods that are controversial because of their safety issues, chemical and physical methods have been developed to enhance gene expression in tissues. Reversible increase of the cell membrane permeability caused by the electric field-electroporation-is currently one of the most efficient and simple non-viral methods of gene transfer," scientists writing in the journal Annals of Biomedical Engineering report.
"We performed a series of in vivo experiments, delivering plasmids to rat skin using external plate electrodes. The experiments showed that skin layers below stratum corneum can be permeabilized in this way. In order to study the...
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Source: Gene Therapy Weekly (2008-02-21)
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