Hepatocellular Cancer

Reports outline hepatocellular cancer study results from University of Milan

Published in Gene Therapy Weekly, February 21st, 2008

"Survivin is an oncofetal protein involved both in cell death and cell cycle regulation. Survivin is undetectable or found at very low levels in normal differentiated tissues whereas increased expression has been observed in several human malignancies, including lung, colon and liver cancer," researchers in Milan, Italy report.

"The aim of this study was to evaluate the diagnostic and clinical significance of Survivin expression in hepatocellular carcinoma and non-neoplastic liver tissues in a series of surgical patients. Survivin mRNA levels were quantitated by real time RT-PCR in 25 patients. Survivin mRNA was documented in all liver tissues with significantly higher...

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Source: Gene Therapy Weekly (2008-02-21)

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