Angiogenesis

Scientists at University of Texas publish research in angiogenesis

Published in Gene Therapy Weekly, February 28th, 2008

"We examined a cohort of patients with alveolar soft part Sarcoma (ASPS) treated at our institution and showed the characteristic ASPSCR1-TFE3 fusion transcript in their tumors. Investigation of potential angiogenesis-modulating molecular determinants provided mechanistic and potentially therapeutically relevant insight into the enhanced vascularity characteristic of this unusual tumor," scientists in the United States report.

"Medical records of 71 patients with ASPS presenting at the University of Texas M.D. Anderson Cancer Center (1986-2005) were reviewed to isolate 33 patients with formalin-fixed paraffin-embedded material available for study. RNA extracted from...

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Source: Gene Therapy Weekly (2008-02-28)

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