Gene Therapy
Researchers from University of Minho, Life and Health Sciences Research Institute publish findings in gene therapy
Published in Gene Therapy Weekly, March 6th, 2008
Researchers detail in 'TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas,' new data in gene. According to recent research published in the journal Cancer Genetics and Cytogenetics, "TP53 is a key tumor suppressor gene that encodes a transcriptional factor involved in several cellular mechanisms, including growth arrest, DNA repair, and induction of apoptosis. In addition to TP53 gene mutations, a common polymorphism, Arg72Pro, has been involved in the carcinogenesis process."
"The Pro72 variant has been associated with a slower induction of apoptosis and may influence the risk of cancer development. The role...
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Source: Gene Therapy Weekly (2008-03-06)
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