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RNA Research

Research from University of Pittsburgh, Department of Psychiatry provides new data on RNA research

Published in Gene Therapy Weekly, March 13th, 2008

Researchers detail in 'Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses,' new data in rna research. "Gene expression profiling holds great promise for identifying molecular pathologies of central nervous system disorders. However, the analysis of brain tissue poses unique analytical challenges, as typical microarray signals represent averaged transcript levels across neuronal and glial cell populations," investigators in the United States report.

"Here we have generated ratios of gene transcript levels between gray and adjacent white matter samples to estimate the relative cellular origins of expression. We show that...

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