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New life sciences study findings have been published by scientists at Kansai Medical University, Department of Surgery

Published in Gene Therapy Weekly, March 13th, 2008

Fresh data on life sciences are presented in the report 'Edaravone prevents iNOS expression by inhibiting its promoter transactivation and mRNA stability in cytokine-stimulated hepatocytes.' According to recent research from Osaka, Japan, "Edaravone has an anti-inflammatory effect in experimental models of various organ injuries. We reported that edaravone reduces the induction of inducible nitric oxide synthase (iNOS) as well as pro-inflammatory cytokines in endotoxin-treated rats with partial hepatectomy, leading to the prevention of liver injury."

"Studies were performed to investigate the mechanisms involved in the inhibition of iNOS expression by edaravone in...

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