Published in Gene Therapy Weekly, March 13th, 2008
"Targeting eicosanoid pathways is an obvious choice because 5-lipoxygenase (5-LOX) has been suggested as a tumor promoter in pancreatic carcinogenesis. Here we provide evidence that 15-lipoxygenase- 1 (15-LOX-1) expression and activity may exert antitumorigenic effects in pancreatic cancer. Reverse transcription - polymerase chain reaction ( RTPCR) and Western blot analysis showed...
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