Gene Therapy
Research findings from East China University of Science and Technology, New World Institute of Biotechnology update understanding of gene therapy
Published in Gene Therapy Weekly, March 20th, 2008
Scientists discuss in 'The transduction of His-TAT-p53 fusion protein into the human osteogenic sarcoma cell line (Saos-2) and its influence on cell cycle arrest and apoptosis' new findings in gene therapy. "The p53 gene is a tumor suppressor gene. It encodes a nuclear phosphoprotein p53 involved in the regulation of cell cycle arrest and apoptosis to maintain the genomic integrity of the cell," investigators in Shanghai, People's Republic of China report.
"As mutations of p53 gene are found in most human cancers, p53 protein becomes a hot target in the research of anticancer therapy. In the present study, an 11-amino acid domain of TAT protein which has been...
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Source: Gene Therapy Weekly (2008-03-20)
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