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New life sciences research has been reported by scientists at University of Sao Paulo, Chemistry Institute

Published in Gene Therapy Weekly, March 20th, 2008

Investigators publish new data in the report 'Cwc24p, a novel Saccharomyces cerevisiae nuclear ring finger protein, affects pre-snoRNA U3 splicing.' "U3 snoRNA is transcribed from two intron-containing genes in yeast, snR17A and snR17B. Although the assembly of the U3 snoRNP has not been precisely determined, at least some of the core box C/D proteins are known to bind pre-U3 co-transcriptionally, thereby affecting splicing and 3'-end processing of this snoRNA," scientists in Sao Paulo, Brazil report.

"We identified the interaction between the box C/D assembly factor Nop17p and Cwc24p, a novel yeast RING finger protein that had been previously isolated in a complex with...

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