Gene Therapy
Scientists at University of Pennsylvania report research in gene therapy
Published in Gene Therapy Weekly, April 3rd, 2008
Scientists discuss in 'Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress' new findings in gene therapy. "Heme oxygenase-1 (HO-1) catalyzes the degradation of heme and forms antioxidant bile pigments as well as the signaling molecule carbon monoxide. HO-1 is inducible in response to a variety of chemical and physical stress conditions to function as a cytoprotective molecule," scientists writing in the journal Free Radical Biology & Medicine report.
"Therefore, it is important to maintain the basal level of HO-1 expression even when substrate availability is limited. We hypothesized that the HO-1 protein itself could...
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Source: Gene Therapy Weekly (2008-04-03)
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