Gene Therapy

Research from Uppsala University provides new data about gene therapy

Published in Gene Therapy Weekly, April 17th, 2008

According to a study from Uppsala, Sweden, "We have studied the evolution of a type TV secretion system (T4SS), in Bartonella, which is thought to have changed function from conjugation to erythrocyte adherence following a recent horizontal gene transfer event. The system, called Trw, is unique among T4SSs in that genes encoding both exo- and intracellular components are located within the same duplicated fragment."

"This provides an opportunity to study the influence of selection on proteins involved in host-pathogen interactions. We sequenced the trw locus from several strains of Bartonella henselae and investigated its evolutionary history by comparisons to other...

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Source: Gene Therapy Weekly (2008-04-17)

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