Published in Gene Therapy Weekly, April 17th, 2008
"We have demonstrated that MCF-10F cells, the immortal and non-tumorigenic human breast epithelial cells (HBEC) that are ER alpha-negative and ER beta-positive, are transformed in vitro by 17 beta-estradiol (E-2), generating highly invasive cells that are tumorigenic in severe combined immunodeficient mice....
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